Updated on 2024/02/15

写真a

 
NISHIKAWA Kahoko
 
Organization
Faculty of Commerce Professor
Other responsible organization
Commerce Course of Graduate School of Commerce, Master's Program
Commerce Course of Graduate School of Commerce, Doctoral Program Program
Graduate School of Science and Engineering(General Subjects)
Contact information
The inquiry by e-mail is 《here
External link

Degree

  • 博士(理学) ( お茶の水女子大学大学院(生活環境研究センター) )

  • 修士(家政学) ( お茶の水女子大学大学院(生活環境研究センター) )

Education

  • 2002.3
     

    Ochanomizu University   Graduate School, Doctral Research Course in Human Culture   doctor course   completed

  • 1991.3
     

    Ochanomizu University   Graduate School, Division of Home Economics   master course   completed

  • 1989.3
     

    Hiroshima University   Faculty of Applied Biological Science   graduated

  • 1985.3
     

    山形県立米沢興譲館高等学校   graduated

Research History

  • 2020.1 - 2021.5

    中央大学副学長

  • 2012.4 - 2018.3

    大妻女子大学 非常勤講師

  • 2015.4 - 2017.3

    東京女子大学 非常勤講師

  • 2015.7 -  

    厚生省国立医薬品食品衛生研究所客員研究員

  • 2015.4 -  

    中央大学商学部 教授

  • 2013.7 - 2015.3

    防衛医科大学校救急部 講師(指定)

  • 2013.4 - 2015.3

    中央大学商学部 兼務講師

  • 2004.1 - 2013.6

    防衛医科大学校救急部 助教

  • 2004.1 - 2011.3

    厚生省国立医薬品食品衛生研究所協力研究員

  • 2006.8 - 2007.7

    英国ケンブリッジ大学生化学部客員研究助手

  • 2002.4 - 2003.12

    お茶の水女子大学大学院人間文化研究科人間環境科学専攻 助手

  • 1991.4 - 1995.3

    日本石油株式会社技術商品部 (技術系総合職)

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Professional Memberships

  • 2021.9 - Now

    土木学会

  • 2016 - Now

    日本水環境学会

  • Center for Environmental Information Science

Research Interests

  • microplastic

  • antimicrobial resistance

  • 食環境

  • environmental bacteria

  • environmentally friendly behavior

  • 環境学

Research Areas

  • Life Science / Ecology and environment  / Ecology/Environment

  • Environmental Science/Agriculture Science / Environmental impact assessment  / Environmental impact assessment

Papers

  • Current Status and Issues of Microplastic Pollution Research Reviewed

    Yoshiomi OTSUKA, Hideshige TAKADA, Yasuo NIHEI, Yutaka KAMEDA, Kahoko NISHIKAWA

    Journal of Japan Society on Water Environment   44 ( 2 )   35 - 42   2021.3

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Japan Society on Water Environment  

    DOI: 10.2965/jswe.44.35

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  • Survey on antimicrobial-resistant bacteria in surface water in Tokyo ~The current state of the tendency of antimicrobial-resistance and distribution ~ Reviewed

    環境情報科学 学術研究論文集 32   32   313 - 316   2018.12

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.11492/ceispapers.ceis32.0_313

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  • What Is Consumer-friendly Eco-labelling?

    中央大学社会科学研究所年報   22   51 - 67   2018.9

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  • 環境中に拡散する薬剤耐性菌 ~どうして川や池に存在するのか~

    西川可穂子

    中央大学論集   ( 39 )   17 - 27   2018.2

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  • Pharmacokinetic Properties of Single and Repeated Injection of Liposomal Platelet Substitute in a Rat Model of Red Blood Cell Transfusion-Induced Dilutional Thrombocytopenia. Reviewed

    Hashimoto M, Taguchi K, Ogaki S, Watanabe H, Kinoshita M, Nishikawa K, Takeoka S, Ikeda Y, Handa M, Otagiri M, Maruyama T

    J Pharm Sci.   104 ( 11 )   2015.8

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  • Resveratrol increases CD68+ Kupffer cells colocalized with adipose differentiation-related protein and ameliorates high-fat-diet-induced fatty liver in mice Reviewed

    Kahoko Nishikawa, Keichi Iwaya

    Molecular Nutrition & Food Research 2015   ( 59 )   1155 - 1170   2015.5

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  • Mep72, a Metzincin Protease That Is Preferentially Secreted by Biofilms of Pseudomonas aeruginosa Reviewed

    Ian J. Passmore, Kahoko Nishikawa, Kathryn S. Lilley, Steven D. Bowden, Jade C. S. Chung, Martin Welch

    JOURNAL OF BACTERIOLOGY   197 ( 4 )   762 - 773   2015.2

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:AMER SOC MICROBIOLOGY  

    In this work, we compared the profile of proteins secreted by planktonic and biofilm cultures of Pseudomonas aeruginosa using two-dimensional difference gel electrophoresis (2D-DiGE). This revealed that a novel metzincin protease, Mep72, was secreted during biofilm growth. Subsequent Western blotting and reverse transcription-PCR (RT-PCR) analyses demonstrated that Mep72 was expressed only during biofilm growth. Mep72 has a tridomain structure comprised of a metzincin protease-like domain and two tandem carbohydrate-binding domains. Unlike the only other metzincin (alkaline protease; AprA) in P. aeruginosa, Mep72 is secreted through the type II pathway and undergoes processing during export. During this processing, the metzincin domain is liberated from the carbohydrate-binding domains. This processing may be self-catalyzed, since purified Mep72 autodegraded in vitro. This autodegradation was retarded in the presence of alginate (an extracellular matrix component of many P. aeruginosa biofilms). The expression of full-length mep72 in Escherichia coli was toxic. However, this toxicity could be alleviated by coexpression of mep72 with the adjacent gene, bamI. Mep72 and BamI were found to form a protein-protein complex in vitro. 2D-DiGE revealed that the electrophoretic mobility of several discrete protein spots was altered in the biofilm secretome of an mep72 mutant, including type III secretion proteins (PopD, PcrV, and ExoS) and a flagellum-associated protein (FliD). Mep72 was found to bind directly to ExoS and PcrV and to affect the processing of these proteins in the biofilm secretome. We conclude that Mep72 is a secreted biofilm-specific regulator that affects the processing of a very specific subset of virulence factors.

    DOI: 10.1128/JB.02404-14

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  • Treatment with fibrinogen gamma-chain peptide-coated, ADP-encapsulated liposomes as an infusible haemostatic agent against active liver bleeding in acute thrombocytopenic rabbits. Reviewed

    Hagasawa K

    Transfusion   2015 ( 55 )   314 - 26   2015.2

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  • Detection of changes in the structure and distribution map of triacylglycerol in fatty liver model by MALDI-SpiralTOF Reviewed

    Kahoko Nishikawa, Masahiro Hashimoto, Yoshiyuki Itoh, Sadayuki Hiroi, Akihiko Kusai, Fumihiko Hirata, Toshihisa Sakamoto, Keiichi Iwaya

    FEBS OPEN BIO   4   179 - 184   2014

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER SCIENCE LONDON  

    Matrix-assisted laser desorption/ ionisation spiral orbit-type time-of-flight mass spectrometry (MALDI-SpiralTOF) can analyse lipid profiles and characterise lipid structure. Imaging mass spectrometry (IMS) also provides distribution maps of selected m/z values. Here, we investigated triacylglycerol (TG) structure and distribution using these technologies to estimate mouse fatty liver. The distribution and intensity of the most intense mass spectrum ion was indicated by IMS at m/z 881.7 (52:2). Analysis using MS/MS showed a structural change between liver TG and dietary TG. These findings suggest that MALDI-SpiralTOF is a powerful tool for clinical screening and estimating fatty liver. (C) 2014 The Authors. Published by Elsevier B.V. on behalf of Federation of European Biochemical Society.

    DOI: 10.1016/j.fob.2014.02.005

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  • 人工血小板H12(ADP)リポソームを用いた急性血小板減少病態への止血・救命対策 Reviewed

    西川可穂子ほ

    人工血液   21 ( 1 )   60 - 67   2013.12

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:日本血液代替物学会  

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  • ビタミンE同族体が高脂肪食誘導性肥満マウスの耐糖能に及ぼす影響 Reviewed

    近松出穂

    ビタミン   86 ( 12 )   671 - 677   2012.12

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:日本ビタミン学会  

    We investigated the effect of vitamin E isoforms on the glucose tolerance in high-fat-induced obese mice. Eighteen male C57BL/6J mice aged six weeks were divided into three groups and fed a high-fat diet without vitamin E (HF), HF supplemented with 0.1% α-tocopherol (α-Toc) or HF supplemented with 0.1% γ-tocotrienol (γ-T3) for ten weeks. Oral glucose tolerance and insulin tolerance were tested after nine weeks of experimental diet feeding. Although growth rate and food intake were not significantly different among the three groups, addition of γ-T3, but not α-Toc, improved glucose tolerance and insulin sensitivity induced by the high-fat diet in obese mice. Fasting insulin levels in the γ-T3 group were lower than those in other high-fat groups, and the level of insulin secretion following glucose loading was significantly higher in the γ-T3 group than in the HF group. Histological findings showed that islets of the γ-T3 group were sufficiently active to secrete insulin in spite of high-fat feeding. These results suggested that γ-T3, but not α-Toc, protected islets against lipotoxicity and could be effective in treating type 2 diabetes.

    DOI: 10.20632/vso.86.12_671

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    Other Link: http://search.jamas.or.jp/link/ui/2013130601

  • 人工赤血球や人工血小板を用いた出血性ショック治療(総説) Reviewed

    木下学ほか

    Surgical Trauma & Immunological Responses   21 ( 3 )   48 - 52   2012.11

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Tōkyō Mejikaru Byūsha  

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  • Fibrinogen gamma-chain peptide-coated, ADP-encapsulated liposomes rescue thrombocytopenic rabbits from non-compressible liver hemorrhage Reviewed

    K. Nishikawa, K. Hagisawa, M. Kinoshita, S. Shono, S. Katsuno, M. Doi, R. Yanagawa, H. Suzuki, K. Iwaya, D. Saitoh, T. Sakamoto, S. Seki, S. Takeoka, M. Handa

    JOURNAL OF THROMBOSIS AND HAEMOSTASIS   10 ( 10 )   2137 - 2148   2012.10

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:WILEY-BLACKWELL  

    . Background: We developed a fibrinogen ?-chain (dodecapeptide HHLGGAKQAGDV [H12])-coated, ADP-encapsulated liposome (H12-[ADP]-liposome) that accumulates at bleeding sites via interaction with activated platelets via glycoprotein IIbIIIa and augments platelet aggregation by releasing ADP. Objective: To evaluate the efficacy of H12-(ADP)-liposomes for treating liver hemorrhage in rabbits with acute thrombocytopenia. Methods: Thrombocytopenia (platelets < 50 000 mu L-1) was induced in rabbits by repeated blood withdrawal (100 mL kg-1 in total) and isovolemic transfusion of autologous washed red blood cells. H12-(ADP)-liposomes with platelet-poor plasma (PPP), platelet-rich plasma (PRP), PPP, ADP liposomes with PPP or H12-(PBS)-liposomes/PPP, were administered to the thrombocytopenic rabbits, and liver hemorrhage was induced by penetrating liver injury. Results: Administration of H12-(ADP)-liposomes and of PRP rescued all thrombocytopenic rabbits from liver hemorrhage as a result of potent hemostasis at the liver bleeding site, although rabbits receiving PPP or ADP liposomes showed 20% survival in the first 24 h. Administration of H12-(ADP)-liposomes and of PRP suppressed both bleeding volume and time from the site of liver injury. H12-(phosphate-buffered saline)-liposomes lacking ADP also improved rabbit survival after liver hemorrhage, although their hemostatic effect was weaker. In rabbits with severe thrombocytopenia (25 000 platelets mu L-1), the hemostatic effects of H12-(ADP)-liposomes tended to be attenuated as compared with those of PRP treatment. Histologic examination revealed that H12-(ADP)-liposomes accumulated at the bleeding site in the liver. Notably, neither macrothombi nor microthrombi were detected in the lung, kidney or liver in rabbits treated with H12-(ADP)-liposomes. Conclusions: H12-(ADP)-liposomes appear to be a safe and effective therapeutic tool for acute thrombocytopenic trauma patients with massive bleeding.

    DOI: 10.1111/j.1538-7836.2012.04889.x

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  • Stathmin is involved in the cooperative effect of Zoledronic acid and gefitinib on bone homing breast cancer cells in vitro Reviewed

    Miki Oda, Keiichi Iwaya, Ryokoki Kuchi, Takayuki Kobayashi, Toshiyuki Yoneda, Kahoko Nishikawa, Osamu Matsubara, Norio Kohno

    Journal of Bone Oncology   1 ( 2 )   40 - 46   2012

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    Zoledronic acid (Zol) is the most potent inhibitor of bone resorption among the bisphosphonates and is commonly used for inhibiting bone metastasis. However, it remains unclear whether Zol provides a survival benefit. Recent findings indicate that epidermal growth factor (EGF) signaling is an important mediator of bone metastasis. Thus, we examined the combined effects of Zol and an EGF receptor-tyrosine kinase inhibitor, gefitinib, on the proliferation and invasion of a bone-seeking clone and the breast cancer cell line MDA-MB-231. Combined treatment with Zol and gefitinib synergistically inhibited both invasion and cell proliferation of the bone-seeking clone, but not those of the MDA-MB-231 cells. Two-dimensional difference gel electrophoresis and mass spectrometry demonstrated that stathmin was down-regulated during these cooperative effects. Stathmin is a signal transduction regulatory factor which plays an important role in cell division and malignant tumor development. Our data suggest that stathmin may be a promising target molecule for blocking bone metastasis of breast cancer. © 2012 Elsevier GmbH. All rights reserved.

    DOI: 10.1016/j.jbo.2012.06.001

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  • 大量出血に伴う急性血小板減少病態に対する人工血小板H12(ADP)リポソームを用いた止血救命対策 Reviewed

    西川可穂子ほ

    Shock   26 ( 2 )   4 - 15   2011.12

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  • 血液希釈による致死性低ヘモグロビン血症とvital organsでのHlF-1α蛋白発現 Reviewed

    木下学ほか

    Shock   26 ( 1 )   32   2011.11

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  • Novel technique of overlaying a poly-l-lactic acid nanosheet for adhesion prophylaxis and fixation of intraperitoneal onlay polypropylene mesh in a rabbit model Reviewed

    Keiichi Fujino, Manabu Kinoshita, Akihiro Saitoh, Hidekazu Yano, Kahoko Nishikawa, Toshinori Fujie, Keiichi Iwaya, Minoru Kakihara, Shinji Takeoka, Daizoh Saitoh, Yuji Tanaka

    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES   25 ( 10 )   3428 - 3436   2011.10

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:SPRINGER  

    Background One problem with polypropylene mesh (PPM) used to repair abdominal wall hernias is dense adhesions to the visceral surface. The authors developed the biocompatible poly-l-lactic acid (PLLA) nanosheet (thickness < 100 nm), which has the unique ability to adhere tightly to tissues but not to opposing tissues. This study investigated the antiadhesive and fixative characteristics of the PLLA nanosheet after placement of intraperitoneal onlay PPM (IPOM) overlaid with a PLLA nanosheet on intact peritoneum.
    Methods The PLLA nanosheet was fabricated by the spin-coating method and peeling technique with polyvinyl alcohol (PVA) as a supporting film. Two 1.5-cm-square pieces of mesh were implanted on each peritoneal side of the midline incision. The mesh was fixed to the peritoneum with a suture and then overlaid with a 4-cm-square piece of Seprafilm or nanosheet. To examine the fixative property, mesh was overlaid with Seprafilm or nanosheet without a fixed suture. After 4 weeks, mesh adhesion, inflammatory reaction, fixation, and dislocation of mesh were evaluated.
    Results Nanosheet-overlaid meshes were flexible and fit over the peritoneum. Adhesion was observed in 10% of the nanosheet-overlaid meshes and in 50% of the Seprafilm-overlaid meshes. The adhesion tenacity grade was significantly lower with the nanosheet-overlaid meshes (0.1 +/- A 0.1) than with the Seprafilm-overlaid meshes (1.0 +/- A 0.4) (p = 0.029), and the percentage of the adhesion area also was lower with the nanosheet-overlaid meshes (1.0 +/- A 1.0% vs 8.5 +/- A 3.2%; p = 0.037). The mean inflammatory cell counts were lower with the nanosheet-overlaid meshes (p = 0.0023). Regarding the fixative property, 37.5% of the nanosheet-overlaid meshes were fixated on the peritoneum, but no Seprafilm-overlaid mesh was fixated.
    Conclusions Overlaying of a PLLA nanosheet was effective for adhesion prophylaxis of intraperitoneal mesh. It also may have a possible beneficial effect on fixation of mesh.

    DOI: 10.1007/s00464-011-1745-7

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  • 食品ロス教育を家庭科教育で Reviewed

    西川可穂子, 藤原葉子, 冨永典子

    日本家政学会誌   62 ( 5 )   299 - 307   2011.5

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  • Detection of bacteria on central venous catheters in a trauma care unit (prospective study) Reviewed

    Nishikawa K

    Journal of the National Defense Medical College   36 ( 1 )   8 - 14   2011.3

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  • Two cases of acute poisoning with acetamiprid in humans Reviewed

    Tomonori Imamura, Youichi Yanagawa, Kahoko Nishikawa, Naoto Matsumoto, Toshihisa Sakamoto

    CLINICAL TOXICOLOGY   48 ( 8 )   851 - 853   2010.10

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:INFORMA HEALTHCARE  

    Introduction. Acetamiprid is a potent and a relatively new neonicotinoid insecticide. Animal studies have indicated that it has a low toxicity to mammals. Despite wide usage, human exposure resulting in toxicity is quite limited, and this is the first report in the English literature about acute acetamiprid poisoning in humans. Case Details. We herein describe two cases of acute poisoning with an insecticide formulation containing acetamiprid for suicidal purposes. Both cases experienced severe nausea and vomiting, muscle weakness, hypothermia, convulsions, and clinical manifestations including tachycardia, hypotension, electrocardiogram changes, hypoxia, and thirst in the case with the higher serum concentration of acetamiprid. The symptoms were partially similar to acute organophosphate intoxication. Supportive treatments for a variety of symptoms were sufficient for recovery, and both individuals were discharged without any complications 2 days after ingestion.</.

    DOI: 10.3109/15563650.2010.517207

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  • Deposits on the intraluminal surface and bacterial growth in central venous catheters. Reviewed

    Nishikawa K

    The Journal of hospital infection   75 ( 1 )   19 - 22   2010.3

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  • Variations on a theme: Diverse N-acyl homoserine lactone-mediated quorum sensing mechanisms in Gram-negative bacteria Reviewed

    Debra Smith, Jin-Hong Wang, Jane E. Swatton, Peter Davenport, Bianca Price, Helga Mikkelsen, Hannah Stickland, Kahoko Nishikawa, Noémie Gardiol, David R. Spring, Martin Welch

    Science Progress   89 ( 4 )   167 - 211   2007

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Blackwell Scientific Publications  

    Many Gram-negative bacteria employ a mechanism of cell-cell communication known as quorum sensing (QS). The role of QS is to enable the cells in a culture to coordinate their gene expression profile with changes in the population cell density. The best characterized mechanisms of QS employ N-acylated homoserine lactones (AHLs) as signalling molecules. These AHLs are made by enzymes known as LuxI homologs, and accumulate in the culture supernatant at a rate proportional to the increase in cell density. Once the AHL concentration exceeds a certain threshold value, these ligands bind to intracellular receptors known as LuxR homologs. The latter are transcriptional regulators, whose activity alters upon binding the AHL ligand, thereby eliciting a change in gene transcription. Over the last five years, it has become increasingly obvious that this is a rather simplistic view of aHL-dependent QS, and that in fact, there is considerable diversity in the way in which LuxI-R homologs operate. The aim ofthe current review is to describe these variations on the basic theme, and to show how functional genomics is revolutionizing our understanding of QS-controlled regulons.

    DOI: 10.3184/003685006783238335

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  • Phytochelatins do not correlate with the level of Cd accumulation in Chlamydomonas spp. Reviewed

    Kahoko Nishikawa, Ai Onodera, Noriko Tominaga

    CHEMOSPHERE   63 ( 9 )   1553 - 1559   2006.6

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:PERGAMON-ELSEVIER SCIENCE LTD  

    Chlamydomonas acidophila KT-1 and Chlamydomonas acidophila DVB238 exhibit a strong heavy metal tolerance, but C acidophila DVB238 can accumulate a much higher amount of Cadmium (Cd) than C. acidophila KT-1. Phytochelatins (PCs) are known to play an important role in the detoxification of several toxic heavy metals, but the relationship between PCs and Cd accumulation is not clear. PC metabolism and Cd accumulation were investigated by using three Chlamydomonas strains including Chlamydomonas reinhardtii C-9 as a standard alga. The results showed that the PC content did not correlate closely with the level of Cd accumulation, maintenance of a high GSH level seeming to be more important for Cd accumulation. The ultrastructure of C acidophila KT-1 was extremely disrupted by a great increase in starch granules, which resulted in a moribund state, but hyper-accumulator C acidophila DVB238 did not exhibit an increase in starch granules in its cells, in spite of Cd accumulation in its chloroplasts, cytosol and vacuoles. These results indicated that C acidophila DVB238 probably has a developed detoxification system preventing such as destruction of the cells due to Cd toxicity. (c) 2005 Elsevier Ltd. All rights reserved.

    DOI: 10.1016/j.chemosphere.2005.09.056

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  • Polyphosphate metabolism in an acidophilic alga Chlamydomonas acidophila KT-1 (Chlorophyta) under phosphate stress Reviewed

    K Nishikawa, H Machida, Y Yamakoshi, R Ohtomo, K Saito, M Saito, N Tominaga

    PLANT SCIENCE   170 ( 2 )   307 - 313   2006.2

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER IRELAND LTD  

    In order to study the polyphosphate (PolyP) metabolism in the acidophilic alga, the effect of rapid change of external phosphate concentration (so-called Pi stress condition) on the distribution of PolyP in Chlamyclomonas acidophila KT-1 was investigated by fluorescent microscopy, in vivo P-31 NMR spectroscopy, and enzymatic quantification. The PolyP granules inside of C acidophila KT-I cells were observed by microscopy with a fluorescent dye 4',6-diarnidino-2-phenylindole (DAPI). Cells transferred from phosphate (Pi) deficient to Pi rich conditions were contained a large amount of PolyP and an additional new PolyP stain was observed around the cell surface. In comparison to a neutrophilic alga Chlamydomonas reinhardtii C-9, the total amount of PolyP in C. acidophila KT-1 was 2.5 times smaller. The lower content of PolyP in C. acidophila KT-1 was supposed to be attributable to the specific properties of its cell membrane, which limited to incorporate phosphate from the environment. Nevertheless, the trend of degradation and re-synthesis of PolyP in C. acidophila KT-1 was similar to that of C reinhardtii C-9 under Pi stress conditions with absolute PolyP amount being affected by the total phosphate in the cells. (c) 2005 Elsevier Ireland Ltd. All rights reserved.

    DOI: 10.1016/j.plantsci.2005.08.025

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  • Ultrastructural changes in Chlamydomonas acidophila (Chlorophyta) induced by heavy metals and polyphosphate metabolism Reviewed

    K Nishikawa, Y Yamakoshi, Uemura, I, N Tominaga

    FEMS MICROBIOLOGY ECOLOGY   44 ( 2 )   253 - 259   2003.5

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER SCIENCE BV  

    Ultrastructural changes induced by heavy metals (cadmium, zinc, and copper) and polyphosphate metabolism were studied in Chlamydomonas acidophila. Transmission electron microscopy indicated that cadmium led to the most drastic morphometric changes. An increase in number and volume of starch grains and vacuoles as well as the presence of electron dense deposits in vacuole and membrane whorls were observed. Energy-dispersive X-ray analysis revealed that vacuolar deposits inside cells treated with cadmium contained phosphate and cadmium. These ultrastructural changes were accompanied by a change in the intracellular polyphosphate level, as shown by in vivo P-31-nuclear magnetic resonance. It was also observed that cadmium treatment caused polyphosphate degradation and increased vacuolar short-chains and orthophosphates. (C) 2003 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

    DOI: 10.1016/S0168-6496(03)00049-7

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  • Isolation, growth, ultrastructure, and metal tolerance of the green alga, Chlamydomonas acidophila (Chlorophyta) Reviewed

    K Nishikawa, N Tominaga

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   65 ( 12 )   2650 - 2656   2001.12

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:TAYLOR & FRANCIS LTD  

    An acidophilic volvocine flagellate, Chlamydomonas acidophila (Volvocales) that was isolated from an acid lake, Katanuma, in Miyagi prefecture, Japan was studied for growth, ultrastructural characterization, and metal tolerance. Chlamydomonas acidophila is obligately photoautotrophic, and did not grow in the cultures containing acetate or citrate even in the light. The optimum pH for growth was 3.5-4.5. To characterize metal tolerance, the toxic effects of Cd, Co, Cu, and Zn on this alga were also studied. Effective metal concentrations, which limited the growth by 50%, EC50 were measured, after 72 h of static exposure. EC(50)s were 14.4 mum Cd2+, 81.3 mum Co2+, 141 mum, Cu2+, and 1.16 mum Zn2+ for 72 h of exposure. Thus, this alga had stronger tolerance to these metals than other species in the genus Chlamydomonas.

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Books

  • シリーズ「おもしろサイエンス 機能野菜の科学」

    佐竹元吉監修( Role: Joint author)

    日刊工業新聞社  2016.5 

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    Language:Japanese   Book type:Scholarly book

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  • In Algae: Nutrition, Pollution Control and Energy Sources.

    NISHIKAWA, K, TOMINAGA, N, UCHINO, T, OIKAWA, A, TOKUNAGA, H( Role: Joint editorChapter 2., p.13-21,Polyphosphate contributes to Cd tolerance in Chlamydomonas acidophila KT-1)

    Nova Science Publishers, Inc. NY,  2009.2 

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MISC

  • THE CHANGES IN CONSUMER AWARENESS AND THE USE OF HOME MEAL REPLACEMENT DURING THE COVID-19 PANDEMIC

    WANG Xuantong, 西川可穂子, 大塚佳臣

    環境システム研究論文発表会講演集   49th (CD-ROM)   2021

  • 水環境中における薬剤耐性菌の実体と今後の対応 Invited

    西川可穂子

    化学物質と環境(エコケミストリー研究会)   161   11 - 12   2020.5

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  • 研究報告書:大量出血合併急性出血性減少家兎モデルにおけるH12(ADP)リポソームの投与効果 - 臓器出血後のH12(ADP)リポソーム事後投与の救命効果とfibrinogen補充の影響 -

    木下学, ほか

    2014.3

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  • 研究報告書:大量出血合併急性出血性減少家兎モデルにおけるH12(ADP)リポソームの投与効果 - 臓器出血後のdamege control surgeryとH12(ADP)リポソーム投与での救命効果

    木下学, ほか

    2013.3

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  • 研究報告書:外傷性大量出血時の易出血性病態に対するH12(ADP)リポソームの止血制御効果 -臓器出血後の投与効果についてー

    木下学, ほか

    2012.3

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  • 研究報告書:H12(ADP)リポソームの人工血小板としての前臨床評価 (効力と安全性)

    木下学, ほか

    2012.3

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  • 研究報告書:好中球機能を用いた血小板減少・外傷性出血における人工血小板投与のin vivo評価

    鈴木克彦, ほか

    2012.3

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  • FIBRINOGEN GAMMA-CHAIN PEPTIDE-COATED, ADENOSINE DIPHOSPHATE-ENCAPSULATED LIPOSOMES RESCUE THROMBOCYTOPENIC RABBITS FROM NON-COMPRESSIBLE LIVER HEMORRHAGE

    K. Nishikawa, K. Hagisawa, T. Sakamoto, M. Kinoshita

    SHOCK   37   15 - 15   2012

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  • 研究報告書:外傷性大量出血時の易出血性病態に対するH12(ADP)リポソームの止血制御効果

    木下学, ほか

    2011.3

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  • 研究報告書:外傷性大量出血時の易出血性病態に対するH12(ADP)リポソームの効果(予後や止血効果、循環動態への影響について)

    木下学, ほか

    2010.3

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  • Effects of metal stress on inorganic polyphosphate in Chlamydomonas acidophila

    K Nishikawa, Tominaga, N

    Journal of Plant Research   ( 115 )   86   2002.12

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  • Characterization and purification of acid phosphatases from acidophilic alga, Chlamydomonas acidophila.

    Machida, H, K Nishikawa, Tominaga, N

    Journal of Plant Research   ( 114 )   77   2001.12

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  • Heavy metal tolerance of the green alga Chlamydomonas acidophila

    K Nishikawa, Ozaki, N, Tominaga, N

    Journal of Plant Research   ( 114 )   74 - 75   2001.12

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Presentations

  • Study of Riverine Llitter Composition and Generation

    Kahoko Nishikawa

    Capacity Building on Marine Debris Management and Monitoring from Source as River is the Major Transport Pathway  2022.10 

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  • Survey of microplastic pollution in the Tama River

    K Nishikawa, H Niimi, T Matsutani, S Inagaki

    Plastic Pollution in Asian Waters 2022  2022.3 

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  • Correlation between Anthropogenic Pollution Index and Antimicrobial-resistant Bacteria in the Urban River, Tokyo

    Kahoko NISHIKAWA, Takayoshi SUZUKI

    Water and Environment Technology Conference online2021  2021.8 

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  • 河川の環境DNAから読み解く薬剤耐性の現状とその考え方

    西川可穂子, 鈴木孝昌

    第21回日本水環境学会シンポジウム講演  2018.9 

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  • Resistome analysis of surface water from two ponds and two rivers in Tokyo.

    K Nishikawa, T Suzuki T

    SETAC Europe 28th Annual Meeting, short abstract p491 WE285 (Rome)  2018.5 

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  • 環境ラベルの認知度は環境配慮商品の購買を促進するか

    西川可穂子, 堀田のぞみ

    第13回日本LCA学会研究発表会  2018.3 

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  • 東京都内の河川等から分離される薬剤耐性菌―耐性薬剤とその分布―

    岩井拓海, 金子直樹, 蜂谷真基, 小山優花, 松田友花, 西川可穂子

    第14回環境情報科学ポスターセッション  2017.12 

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  • Frequency of antimicrobial resistance in bacteria at urban pond and river in Tokyo.

    K Nishikawa, T Suzuki T, Iwai Y Koyama, N Kaneko, M Hachiya

    The 18th International Conference on Diffuse Pollution and Eutrophication (LA 2017)(oral presentation)  2017.8 

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  • Resveratrol ameliorates high fat diet-induced fatty liver with alteration of Kupffer cell subset in mice.

    西川可穂子, ほか

    4rh European Congress of Immunology, Vienna 2015  2015.9 

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  • Resveratrol increase CD68+Kupffer cells co-localized with adipose differentiation-related protein (adfp) and ameliorates high-fat-diet-induced fatty liver in mice.

    K Nishikawa, K. Iwaya, M. Hashimoto, Y.Fujiwara, S. Thiuppathi, T Suzuki, S Seki, T.Sakamoto

    4th European Congress of Immunology 2015 (Vienna)  2015.9 

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  • 出血性ショック時の蘇生輸血(赤血球、血小板、血漿の1:1:1輸血)と血液代替物使用の可能性

    萩沢康介, 木下学, 西川可穂子, 柳川錬平, 多喜川真人, 土井麻美, 武岡真司, 半田誠, 齋藤大蔵, 関修司, 西田育弘

    第21回日本血液代替物学会  2014.12 

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  • Resveratrol ameliorates fatty liver by reducing the size of lipid droplet without changing liver fat species.

    K Nishikawa, M. Hashimoto, Y. Itoh, S. Hiroi, T.Sakamoto, K. Iwaya

    FEBS EMBO 2014 Conference  2014.9 

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  • Oxidative stress induced by hemorrhage shock and the effect of hypothermia treatment

    Sakamoto K, その他

    The 17th Biennial Meeting of Society for Free Radical Research International. Journal of Clinical Biochemistry and Nutrition  2014.3 

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  • 出血性ショックによる参加ストレスの亢進と低体温療法やコエンザイムQ10投与の効果

    坂本賢その

    第11回日本コエンザイムQ10協会研究会  2014.1 

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  • Resveratrol increases CD68 positive Kupffer cells with phagocytic activity to lipid droplets and ameliorates high-fat diet induced fatty liver in mice.

    Nishikawa K

    第42回日本免疫学会総会学術集会  2013.12 

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  • 急性血小板減少病態に対するナノ粒子H12(ADP)リポソーム製剤を用いた止血救命対策

    西川可穂子

    日本救急医学会  2013.10 

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  • 人工血小板H12(ADP)リポソームの急性血小板減少家兎での肝臓出血後の投与における止血・救命効果の検討

    西川可穂子そ

    日本shock学会  2013.5 

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  • 食餌性レスベラトロールが肝臓に蓄積する中性脂肪へ与える影響

    西川可穂子そ

    第67 回日本栄養食糧学会大会  2013.5 

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  • Resveratrol ameliorates high fat diet-induced fatty liver with alteration of Kupffer cell subset in mice.

    Nishikawa K

    Immunology 2013  2013.5 

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  • Artifcial Platelet for Hemostasis in Severe Injury.

    Hagisawa K

    2013.3 

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  • 血小板代替物H12ADP リポソーム開発の必要性、大規模災害時への対策の1 つとして

    木下学その

    日本血液代替物学会  2012.10 

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  • 大量出血後輸液による血小板減少状態下で進行する肝外傷出血に対してH12(ADP)リポソーム同時投与は血小板投与と同等の止血および救命効果を有する

    萩沢康介そ

    日本血液代替物学会  2012.10 

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  • Fibrinogen Gamma-Chain Peptide-Coated, Adenosine Diphosphate-Encapsulated Liposomes Rescue Thrombocytopenic Rabbits from Non-Compressible Liver Hemorrhage.

    Nishikawa K, K. Hagisawa, T. Sakamoto, M. Kinoshita

    7th Congress of the International Federation of Shock Societies and 35th Annual Conference on Shock Abstract  2012.6 

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  • 人工血小板H12(ADP)リポゾームを用いた血小板減少病態時の臓器外傷部位における止血制御の有効性 (出血後投与による検討)

    西川可穂子 その他

    日本shock学会  2012.5 

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  • ナノコラーゲンペプチドの塗布および経口摂取が皮膚に及ぼす影響

    西川可穂子ら

    第66 回日本栄養食糧学会大会  2012.5 

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  • コラーゲンポリ乳酸ナノシートを用いたメッシュの固定性に関する実験的検討

    藤野啓一ら

    日本外科学会  2012.4 

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  • Crystal deposits on the surface of catheters derived from administration of solution facilitated bacterial propagation even in the antimicrobial catheters

    西川可穂子, 阪本敏久

    日本農芸化学会平成24年度大会  2012.3 

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  • 高脂肪食マウスの肝脂質代謝とクッパー細胞に与えるレスベラトロールの影響

    西川可穂子ら

    防衛衛生学会  2012.2 

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  • Synthetic Platelet H12-(ADP)liposomes Rescue Thrombocytopenic Rabbits from Non-compressible Liver Bleeding.

    Handa M, Nishikawa K, Takeoka S, Kinoshita M

    AABB annual meeting & cttxpo 2011  2011.10 

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  • Crystal deposits on the surface of antimicrobial central venous catheters derived from administration of total parenteral nutrient solution impair antimicrobial efficacy.

    Nishikawa K et al.

    IV Internation Conference on Environmental, Industrial and Applied Microbiology. Book of Abstracs.  2011.9 

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  • 高脂肪食マウスの肝脂質代謝に与えるレスベラトロールの影響

    西川可穂子そ

    第65回日本栄養・食糧学会大会  2011.5 

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  • 脂肪酸がマウス由来C2C12細胞に与える影響;DNAマイクロアレイによる網羅的解析

    齋藤可奈子そ

    第65回日本栄養・食糧学会大会  2011.5 

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  • γ-トコトリエノールが耐糖能に及ぼす影響の検討

    近松出穂ら

    第65回日本栄養・食糧学会大会  2011.5 

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  • ResveratrolとStilbene誘導体がマウス由来C2C12細胞に及ぼす影響

    栗原千明そ

    第65回日本栄養・食糧学会大会  2011.5 

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  • 大量出血に伴う急性血小板減少病態に対する人工血小板H12(ADP)リポソームに用いた止血救命対策

    西川可穂子そ

    日本Shock学会  2011.5 

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  • 血液稀釈による致死性ヘモグロビン血症tpvital organsでのHIF-1α蛋白発現

    木下学その

    日本Shock学会  2011.5 

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  • Adhision Prophylaxis and Fixation of Polypropylene Mesh on Rabbit Abdominal Wall using Poly l-Lactic Acid (PLLA) Nanosheet.

    Fujino K, その他

    14th Annual Hernia Repair. Hernia 15  2011.3 

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  • Fixation of polypropylene mesh on the rabbit abdominal wall using poly L-Lactic acid (PLLA) nanosheet.

    Fujino K, その他

    SAGES2011 (San Diego) Abstract ID: 32927  2011.3 

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  • Mutanase From Fermented Soybeans Solubilizes Biofilms Formed By Cariogenic Streptococci

    Tsumori H, その他

    International Association for Dental Research 89th  2011.3 

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  • 人工血小板による止血制御

    萩沢康介そ

    防衛衛生学会  2011.2 

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  • 熱傷受傷後の肝臓タンパクプロファイルの変化

    西川可穂子そ

    防衛衛生学会  2011.2 

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  • 外傷性大量出血時の大量輸血に伴う血小板減少病態時の人工血小板H12(ADP)liposomeによる止血制御効果

    西川可穂子

    日本血液代替物学会  2010.10 

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  • Liposome-encapsulated Hb (LEH)の動物モデルでの投与成績—血液交換モデル、経骨輸血モデルでの知見—

    木下学その

    日本血液代替物学会  2010.10 

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  • 人工血小板H12(ADP)リポゾームを用いた外傷性大量出血に伴う血小板減少時の止血制御に関する研究

    西川可穂子

    日本shock学会  2010.5 

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  • ICUにおける中心静脈カテーテルの留置期間と感染

    西川可穂子そ

    日本細菌学会  2010.3 

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  • 高脂肪食マウス肝臓におけるプロテオーム解析 -食餌性レスベラトロールの評価―

    西川可穂子

    日本農芸化学会平成22年度大会  2010.3 

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  • 重金属耐性好酸性緑藻Chlamydomonas acidophila DVB238のgamma-glutamylcysteine synthetase (EC.6.3.2.2)(GCS)遺伝子の解析およびCd蓄積関連物質の探索

    石川久美子, 嶋田勢津子, 西川可穂子, 冨永典子

    日本植物学会第73回大会  2009.9 

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  • Paenibacillus humicus 産生グルカナーゼの精製と遺伝子のクローニング

    津守秀明, 西川可穂子, 花田信弘

    日本細菌学会  2009.3 

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  • Electron microscopic examination of central venous catheter: Co deposits fixed on the lumen act as hotbeds of bacterial propagation?

    Nishikawa K

    Critical Care Medicine  2009.2 

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  • Characteristics and phylogeny of an acidophilic and halotolerant green alga, Dunaliella sp. LG-2

    Nishikawa K, その

    The British Phycological Society 57th Winter Meeting, programme & Abstract Booklet  2009.1 

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  • CVカテーテルに局在する細菌と薬剤耐性

    西川可穂子

    日本細菌学会  2008.3 

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  • 緑膿菌のバイオフィルム形成時における分泌たんぱく質の網羅的解析

    西川可穂子, 阪本敏久

    日本農芸化学会平成20年度大会  2008.3 

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  • カドミウム高蓄積性好酸性緑藻Chlamydomonas acidophila のグルタチオン合成酵素遺伝子の解析

    嶋田勢津子, その他

    日本植物学会第71回大会  2007.9 

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  • TRISS法での予後予測に反した症例の報告

    岩本慎一郎そ

    日本外傷学会  2006.5 

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  • 好酸性藻類Chlamydomonas acidophilaのグルタチオン代謝に与えるCdの影響

    西川可穂子, 柳沢芳江, 冨永典子

    日本植物学会第69回大会  2005.9 

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  • 好酸性藻類Chlamydomonas acidophila DVB238における重金属蓄積性関連タンパク質の探索

    森田真由美, 西川可穂子, 冨永典子

    日本植物学会第69回大会  2005.9 

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  • 日本産およびイタリア産の好酸性藻類における重金属蓄積機構関連タンパク質の比較と探索

    細見沙織そ

    第46回日本植物生理学会年会  2005.3 

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  • Phytochelatin synthesis in Chlamydomonas acidophila KT-1 and C. acidophila DVB238

    Nishikawa K, Onodera A, Tominaga N

    The 1st International conference on Environmental Industrial and Applied Microbiology  2005.3 

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  • Polyphosphate degradation and exopolyphosphatase activities under heavy metal in Chlamydomonas acidophila

    Nishikawa K, Oikawa A, Tominaga N

    The 11th International conference on the Cell & Molecular Biology of Chlamydomonas  2004.6 

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  • 好酸性緑藻の金属ストレスによるポリリン酸分解について

    西川可穂子, 及川歩美, 冨永典子

    日本農芸化学会平成16年度大会  2004.3 

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  • 好酸性単細胞緑藻Chlamydomonas acidophila Negoroの環境ストレス応答について

    小野寺愛衣, 長尾明子, 西川可穂子, 冨永典子

    日本植物学会第67回大会  2003.9 

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  • 単細胞緑藻Chlamydomonasの好酸性株における分子系統学的解析

    細見沙織

    日本植物学会第67回大会  2003.9 

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  • 外部リン酸濃度変化におけるChlamydomonas acidophilaChlamydomonas reinhardtiiのポリリン酸代謝

    西川可穂子, 町田春子, 大友量, 冨永典子

    日本植物学会第67回大会  2003.9 

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  • Polyphosphate metabolism in Chlamydomonas acidophila in phosphate-limited conditions under heavy metal (Cd) stress

    Nishikawa K, Yamakoshi Y, Ohtomo R, Tominaga N

    Plant Biology 2003  2003.7 

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  • 好酸性緑藻Chlamydomonas acidophilaの重金属蓄積能とポリリン酸代謝の解析

    西川可穂子, 内野正, 徳永裕司, 冨永典子

    日本農芸化学会平成15年度大会  2003.3 

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  • 単細胞緑藻の重金属ストレスによるポリリン酸代謝

    西川可穂子, 冨永典子

    日本植物学会第66回大会  2002.9 

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  • Change of ultrastructure and accumulation of polyphosphates in Chlamydomonas acidophila

    Nishikawa K, Tominga N, Yamakoshi Y, Ohtomo R

    The 10th International conference on the Cell & Molecular Biology of Chlamydomonas  2002.6 

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  • 重金属暴露による単細胞緑藻の微細構造変化について

    西川可穂子, 冨永典子

    日本農芸化学会平成14年度大会  2002.3 

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  • 好酸性単細胞緑藻Chlamydomonas acidophilaの重金属耐性について

    西川可穂子, 尾崎典子, 冨永典子

    日本植物学会第65回大会  2001.9 

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  • 好酸性単細胞緑藻Chlamydomonas acidophilaの酸性ホスファターゼについて

    町田春子, 西川可穂子, 冨永典子

    日本植物学会 第65回大会  2001.9 

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  • 耐塩性好酸性Chlamydomonas sp.の酸性ホスファターゼについて

    西川可穂子, 冨永典子

    日本農芸化学会平成元年度大会  1989.3 

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Awards

  • International Activity Award

    2021.3   Japan Society on Water Environment  

  • 第2回薬剤耐性(AMR)対策普及啓発活動表彰 文部科学大臣賞

    2018.11   文部科学省   都内表層水の薬剤耐性菌の調査と薬剤耐性菌についての知識の普及活動

    中央大学全学連携教育環境プログラム西川ゼミの薬剤耐性菌に関する取り組み

  • New Investigators Travel Award

    2012.8   The international Federation of Shock Societies   "Fibrinogen Gamma-Chain Peptide-Coated, Adenosine Diphosphate-Encapsulated Liposomes Rescue Thrombocytopenic Rabbits from Non-Compressible Liver Hemorrhage."

  • 日本Shock学会会長賞

    2012.5   日本Shock学会   大量出血に伴う急性血小板減少病態に対する人工血小板H12(ADP)リポソームを用いた止血救命対策

  • Travel award

    2002.6   The Chlamydomonas research community   Change of ultrastructure and accumulation of polyphosphates in Chlamydomonas

Research Projects

  • Onsite survey of plastic pollution in mangrove ecosystem based on digital image analysis and impact assessment

    Grant number:20KK0247  2020.10 - 2024.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))  The University of Tokyo

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    Grant amount: \18590000 ( Direct Cost: \14300000 、 Indirect Cost: \4290000 )

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  • 都市河川・湖沼への抗生物質拡散と環境微生物生態系への影響を評価する

    2016.4 - 2019.3

    文部科学省  科学研究費補助金(日本学術振興会・文部科学省)-基盤研究(C) 

    西川可穂子

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount: \4940000

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  • 新しい環境技術のための環境評価のあり方とその手法

    2016.4 - 2018.3

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    Grant type:Competitive

    Grant amount: \1500000

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  • Compromised hostへの重度侵襲対策

    2013.4 - 2016.3

    文部科学省  科学研究費補助金(日本学術振興会・文部科学省)-基盤研究(B) 

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    Grant type:Competitive

    Grant amount: \17940000

    救急医学

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  • レスベラトロールによる脂肪肝改善効果の検討 -クッパー細胞の機能と脂質代謝の変化―

    2013.4 - 2015.3

    文部科学省  科学研究費補助金(日本学術振興会・文部科学省)-基盤研究(C) 

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    Grant type:Competitive

    Grant amount: \4000000

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  • HiCEP法と連動したナノスケール次世代解析法の開発:新規主要マーカーの同定と診断への応用

    2012.4 - 2014.3

    防衛省  平成24-26年度 防衛省特別研究費 

    岩屋啓一

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    Grant type:Competitive

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  • リピドミクス解析を用いたレスベラトロールによる脂肪肝改善効果の解明

    2012.4 - 2013.3

    防衛医科大学校  平成24年度奨励研究 

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    Grant type:Competitive

    Grant amount: \1000000

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  • ピロリ菌と胃炎起因菌の共存が胃癌細胞の増殖に与える影響

    2011.4 - 2012.3

    文部科学省  科学研究費補助金(日本学術振興会・文部科学省)-挑戦的萌芽研究 

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    Grant type:Competitive

    Grant amount: \2900000

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  • 外傷性大量出血時の大量輸液に伴う血小板減少病態時の人工血小板 H12(ADP)-liposomeによる止血制御効果

    2011.4 - 2012.3

    防衛医科大学校  平成23年度奨励研究費 

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    Grant type:Competitive

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  • 熱傷後の複合免疫不全病態の解析とその対策

    2010.4 - 2012.3

    文部科学省  科学研究費補助金(日本学術振興会・文部科学省)-基盤研究(C) 

    木下学

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    Grant type:Competitive

    Grant amount: \3000000

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  • メタボリックシンドローム予防と油脂の摂取に関する研究

    2009.4 - 2012.3

    文部科学省  科学研究費補助金(日本学術振興会・文部科学省)-基盤研究(C) 

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    Grant type:Competitive

    食生活学

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  • 国際活動医療研究分野:熱帯感染症に関する研究(I-1)

    2009.4 - 2011.3

    平成21-22年度 防衛医学推進研究費 

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    Grant type:Competitive

    Grant amount: \600000

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  • ラット重症出血性ショックモデルにおけるプロテオミクス解析

    2008.4 - 2009.3

    田辺三菱製薬株式会社  民間助成金 

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    Grant type:Competitive

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  • Virulence factor production by Pseudomonas aeruginosa biofilms

    2007.6 - 2008.9

    The Isaac Newton Grant (UK)  The Isaac Newton Grant (UK) 

    Martin Welch

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    Grant type:Competitive

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Allotted class

  • 2023   環境学   Department

  • 2023   総合講座(商学部メジャー探検講座)   Department

  • 2023   課題演習Ⅰ   Department

  • 2023   課題演習Ⅱ   Department

  • 2023   FLP演習A(環境・社会・ガバナンス)   Department

  • 2023   Global Sustainability Science特別演習Ⅰ   Graduate school

  • 2023   Global Sustainability Science特別演習Ⅱ   Graduate school

  • 2023   Global Sustainability Science特論   Graduate school

  • 2023   基礎セミナー(経済学)   Graduate school

  • 2023   水平和学特別演習Ⅰ   Graduate school

  • 2023   水平和学特別演習Ⅱ   Graduate school

  • 2023   演習Ⅰ(生物多様性の経済的価値)   Graduate school

  • 2023   演習Ⅱ(気候変動と環境変容)   Graduate school

  • 2023   特殊研究Ⅰ(環境と社会)   Graduate school

  • 2023   特殊研究Ⅱ(環境と社会)   Graduate school

  • 2023   特殊研究Ⅲ(環境と社会)   Graduate school

  • 2023   環境・生命特別演習Ⅰ   Graduate school

  • 2023   環境・生命特別演習Ⅱ   Graduate school

  • 2023   生物多様性と経済活動Ⅰ   Graduate school

  • 2023   生物多様性と経済活動Ⅱ   Graduate school

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Academic Activities

  • 八王子市環境審議会委員

    2017.8 -  

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Social Activities

  • 薬が効かない!薬剤耐性の拡大と感染を防ぐには

    Role(s): Lecturer

    中央大学学術講演会  2019.11 -  

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    Type:Lecture

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  • 「環境中における耐性菌の分布とメタゲノム解析から見える微生物生態系への影響」

    Role(s): Lecturer

    日本製薬工業会  第23回環境安全セミナー  製薬協環境ニュースNo.127(2018年3月)p13-17  2017.11    

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    Audience: Company

    Type:Seminar, workshop

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  • チン州の水環境 (分担部分)

    Role(s): Lecturer

    お茶の水女子大学  ミャンマーフォーラム  2014.3    

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    Audience: General

    Type:Lecture

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  • 高脂肪食マウスの肝脂質代謝とクッパー細胞に与えるレスベラトロールの影響

    Role(s): Lecturer

    お茶の水女子大学 生活環境研究センター  頭脳循環を活性化する若手研究者からの研究報告  2012.3    

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    Audience: College students, Graduate students, Researchesrs

    Type:Lecture

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  • 抗菌性カテーテルの抗菌性とバイオフィルム

    Role(s): Lecturer

    第三回埼玉救命救急・集中治療領域耐性菌フォーラム  2011.11    

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    Audience: Company

    Type:Lecture

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  • Omics解析におけるプロテオミクス解析の実際

    Role(s): Lecturer

    自衛隊医学実験隊  2011.1    

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    Audience: Researchesrs

    Type:Lecture

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  • CVカテーテルの内腔表面に局在する細菌と薬剤耐性

    Role(s): Lecturer

    第二回埼玉救命救急・集中治療領域耐性菌フォーラム  2010.11    

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    Audience: Researchesrs, Company

    Type:Lecture

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  • 微生物とは何だろう?何をしているの?

    Role(s): Lecturer

    英国ケンブリッジ州ニューナムクロフト小学校  2007.2    

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    Audience: Schoolchildren

    Type:Visiting lecture

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  • Chlamydomonas acidophila Negoro from Japan

    Role(s): Lecturer

    国立ナポリ大学(ナポリ)  2003.2    

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    Audience: Researchesrs

    Type:Seminar, workshop

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  • 重金属暴露による単細胞緑藻の微細構造変化

    Role(s): Lecturer

    独立行政法人農業技術研究機構 畜産草地研究所  2002.5    

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    Audience: Researchesrs

    Type:Seminar, workshop

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